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Health
Upward of 7.5 million adults live with psoriasis, a chronic skin condition that causes red and scaly patches on the body. Flakes and scales build up on the body, creating thick sections of skin that crack—and sometimes bleed. The most common areas affected by psoriasis are the elbows, scalp, lower back, face, palms of hands, soles of feet, and knees.
The exact cause of psoriasis in a person can be hard to identify, but it is thought to be a combination of genetic susceptibility and certain environmental exposures or triggers—such as infections, medications, other medical conditions, trauma, or other stressors on the body, explains Brandon Cometti, MD, founder of Roswell Skin Care in Roswell, New Mexico. Once triggered, psoriasis involves over-activation of certain inflammatory pathways in the body that lead to the symptoms. Although psoriasis isn't curable, topical treatments can help decrease inflammation, diminish redness, itching, and flaking, nourish the skin, and promote healing.
To find the best lotions and creams to help treat psoriasis, we spoke to dermatologists and researched the most highly recommended products. We also had a board-certified dermatologist on our Medical Expert Board review this article for medical and scientific accuracy.
Our Top Picks
- Best Overall: CeraVe Psoriasis Moisturizing Cream
- Best Budget: Gold Bond Ultimate Psoriasis Relief Cream
- Best with SPF: Aveeno Protect + Hydrate Sunscreen Body Lotion SPF 60
- Best for Plaques: Psoriasis Honey Skin-Renewing Cream
- Best for Under Makeup: TriDerma Psoriasis Control Face and Body Cream
- Best for the Shower: Curél Hydratherapy Itch Defense Wet Skin Moisturizer
- Best with Corticosteroids: Cortizone 10 Anti-Itch Lotion for Psoriasis
- Best Natural: Roycederm Seborrheic Dermatitis Cream Psoriasis Cream
- Best With Salicylic Acid: MG217 Medicated Moisturizing Psoriasis Cream
Ingredients that Help with Psoriasis
A variety of topical creams and ointments exist, and for more severe psoriasis, several systemic medications (pills and injections) can help treat the disease. Lotions, creams, and ointments with specific active ingredients—like salicylic acid and coal tar—can help soften and remove the extra cells. Applying these creams two to four times a day can help reduce symptoms of psoriasis and promote healing. Other treatments may include prescription corticosteroids and retinoids.
Because different types of psoriasis may appear on any location of the body and the disease can vary in severity from person to person, individuals should see a dermatologist who is an expert in psoriasis to receive an accurate diagnosis and appropriate treatment plan, explains Olivia Choi, MD, Ph.D., FAAD, a board-certified dermatologist and medical director of Dermatology at Janssen Pharmaceutical Companies of Johnson & Johnson.
Ingredients to Avoid When Treating Psoriasis
Dr. Choi advises that people with psoriasis avoid harsh or irritating products, such as those containing alcohol, sulfates, fragrances, dyes, preservatives, and parabens. These can all cause skin irritation, which is the last thing you want when treating psoriasis.
Some people may be more sensitive to ingredients than others. If you’re unsure how you’ll react to a certain product or ingredient, consider testing it on a small area of skin before using it.
Best Overall
CeraVe Psoriasis Moisturizing Cream
Why We Like It
CeraVe products have been trusted for years, and its Psoriasis Moisturizing Cream is no exception. This deeply moisturizing cream packs a powerful punch with its combination of three essential ceramides—plus salicylic acid and niacinamide. And since it's non-comedogenic, you can use it without worrying about clogged pores.
Ceramides are known for their ability to hydrate and maintain the skin’s natural barrier, while salicylic acid relieves scaling and discomfort. Niacinamide, an anti-inflammatory and skin-restoring ingredient, enhances this cream’s ability to reduce redness and itching associated with psoriasis.
It’s Worth Noting
It's important to note this product also contains alpha hydroxy acid, which increases your skin's sensitivity to the sun. Be sure to use a broad-spectrum sunscreen and reduce sun exposure while using this cream.
Product Details:
- Form: Cream
- Scent: Fragrance-free
- Key Ingredients: Ceramide 1, 3, and 6-11, 5% Urea, 2% salicylic acid, lactic acid, Niacinamide
- Body area: Arms, legs, body
Best Budget
Gold Bond Ultimate Psoriasis Relief Cream
Why We Like It
Gold Bond is a drugstore staple, and its Ultimate Multi-Symptom Psoriasis Relief Cream is a powerful, budget-friendly option. It contains seven intensive moisturizers, including aloe, shea butter, and jojoba oil, that help restore and maintain your skin's natural barrier. It also contains 3 percent salicylic acid to kick-start the skin's exfoliation of flaky patches.
Recognized by the National Psoriasis Foundation, the ceramides quickly lock in moisture to prevent further irritation and dryness. Finally, the cream contains essential vitamins to calm inflammation—leaving your skin soft and smooth. This fragrance and steroid-free formula is a top choice for those looking to soothe psoriasis flare-ups without breaking the bank.
It’s Worth Noting
It may initially cause a burning sensation during application.
Product Details:
- Form: Cream
- Scent: Fragrance-free
- Key Ingredients: Aloe, shea butter, jojoba oil, 3% salicylic acid, ceramides
- Body Area: Arms, legs, body
Best with SPF
Aveeno Protect + Hydrate Sunscreen Body Lotion
Why We Like It
UV rays are harmful to all skin types, so protecting your skin from the sun is critical to preventing damage. Aveeno Protect + Hydrate Body Sunscreen Lotion does just that. It contains broad spectrum SPF 60 to defend your skin from the sun’s harmful UVA and UVB rays—all while locking in moisture to prevent dryness.
What makes this lotion stand out is its unique prebiotic oat complex. Oats contain anti-inflammatory and skin-restoring properties that ease itching and restore balance to irritated skin. It goes on smoothly, is fast absorbing, and won’t leave behind a white or greasy residue. And since Aveeno products come dermatologist-recommended, you can trust it to keep your psoriasis symptoms in check. Apply 15 minutes before sun exposure and every two hours for optimal coverage.
It’s Worth Noting
This product is not specifically designed to treat psoriasis.
Product Details:
- Form: Lotion
- Scent: Fragrance-free
- Key Ingredients: Broad spectrum SPF 60, prebiotic oat, avobenzone 3%, homosalate 13.5%, octisalate 5%, octocrylene 10%
- Body Area: Arms, legs, body
Best for Plaques
Psoriasis Honey Skin-Renewing Cream
Why We Like It
The Skin-Renewing Cream from Psoriasis Honey helps soothe irritation and heal stubborn plaque psoriasis—a benefit of the active ingredient, salicylic acid. It’s made with a unique blend of natural ingredients like honey, aloe vera, grapeseed oil, and beeswax that help hydrate and nourish your skin without harsh chemicals or fragrances.
Honey is a natural antiseptic and anti-inflammatory that soothes itching, while aloe vera relieves skin irritation and helps reduce redness. Grapeseed oil is rich in vitamins and antioxidants to nourish your skin and promote healing. Its powerful moisturizing properties help restore the skin’s natural barrier to prevent further dryness and flaking. Though the cream has a tacky feel, the thick formula penetrates deep while protecting the outer skin layer from further damage.
It’s Worth Noting
This product contains several oils which create a greasy residue.
Product Details:
- Form: Cream
- Scent: Fragrance-free
- Key Ingredients: Honey, aloe vera, grapeseed oil, beeswax
- Body Area: Arms, legs, body
Best for Under Makeup
TriDerma Face and Body Cream
Why We Like It
Another salicylic acid-based psoriasis cream, TriDerma Psoriasis Control, encourages the repair of damaged skin. Its unique blend of natural ingredients like oat protein, vitamins B and E, and urea visibly softens the skin. Inflammation-reducing aloe vera and beeswax target psoriasis plaques and scales to reveal healthier-looking skin.
Unlike many other creams, TriDerma Psoriasis Control is designed for psoriasis on the face and body, whereas many are solely for the body. We appreciate the non-greasy, lightweight formula that won’t leave behind a heavy residue.
It’s Worth Noting
It's naturally an off-white to gray color—free from synthetic dyes—so it may cause a slight tinge when applied to darker skin tones.
Product Details:
- Form: Cream
- Scent: Fragrance-free
- Key Ingredients: Salicylic acid, oat protein, vitamins B and E, urea, aloe vera, beeswax
- Body Area: Face, arms, legs, body
Best for the Shower
Curél Hydratherapy Itch Defense Wet Skin Moisturizer
Why We Like It
Showering can be an uncomfortable experience for those living with psoriasis, as the hot water can exacerbate dryness and itching. Curél Hydra Therapy is a unique body moisturizer you apply to clean, wet skin directly in the shower. When the lotion contacts water, it instantly becomes a rich cream that penetrates open pores to hydrate quickly.
This product comprises ceramides to restore and strengthen the skin’s natural protective barrier. In addition to its moisturizing benefits, Curél Hydra Therapy also soothes itching and relieves tightness from dryness. It contains vitamin E and oatmeal extract to protect and nourish your skin. Apply the lotion to wet skin and towel dry—no rinsing required.
It’s Worth Noting
Some users have reported issues with the pump bottle breaking.
Product details:
- Form: Lotion
- Scent: Fragrance-free
- Key Ingredients: Ceramides, Vitamin E, oatmeal extract
- Body Area: Arms, legs, body
Best with Corticosteroids
Cortizone 10 Anti-Itch Lotion for Psoriasis
Why We Like It
Corticosteroids are an effective psoriasis treatment, but they come with some downsides—dryness and irritation. Cortizone 10 Anti-Itch Psoriasis Lotion helps to counteract those effects by including seven intensive moisturizers. The lotion also contains a maximum-strength dose of topical hydrocortisone (1 percent) to reduce the swelling, redness, and irritation associated with psoriasis—without harsh side effects.
This product is fast-acting, so you can expect it to begin working within minutes. Plus, it's designed to be used up to four times daily for maximum relief.
It’s Worth Noting
It may cause skin irritation in some, so make sure to test it on a small patch of skin first.
Product Details:
- Form: Lotion
- Scent: Fragrance-free
- Key Ingredients: Topical hydrocortisone (1%), 7 intensive moisturizers
- Body Area: Arms, legs, body
Best Natural
Roycederm Psoriasis Cream
Why We Like It
With over eight herbs and extracts, Roycederm Seborrheic Dermatitis & Psoriasis Cream is a 100 percent natural, non-steroidal solution to psoriasis. As an intensive scalp treatment, it's designed to reduce redness, itching, and flaking associated with scalp psoriasis. Best of all, it's free of synthetic fragrances and dyes that often trigger irritation.
This psoriasis cream contains a blend of herbage extractors, which work on flakes and dandruff buildup. Within days of use, it helps mitigate discomfort and replenish the scalp's moisture barrier. Plus, it's safe to use on other body parts, such as the elbows and knees, where psoriasis is often present.
It’s Worth Noting
A burning sensation may occur for up to 15 minutes after application.
Product Details:
- Form: Cream
- Scent: Herbal scent
- Key Ingredients: Artemisia Extract, Sophora Flavescens, Cnidium Monnieri (L.) Cuss., Kochia scoparia, Dictamni Cortex, Smilax Glabra Roxb, Solidago Decurrens
- Body Area: Scalp, neck, ears, arms, legs, body
Best With Salicylic Acid
MG217 Medicated Psoriasis Cream
Why We Like It
MG217 Medicated Moisturizing Psoriasis Cream offers the best of both worlds with its potent combination of salicylic acid and coal tar. According to the National Psoriasis Foundation, both ingredients are FDA-approved for treating psoriasis. While salicylic acid helps shed dead skin, coal tar slows the growth of diseased cells that form plaques on the skin—a double whammy for those looking for relief.
This psoriasis cream absorbs quickly to lock in moisture, soothe inflammation, and reduce redness. However, the makers also sell other psoriasis products that complement the cream—such as scalp shampoo, conditioner, and ointment. We appreciate the added moisturizers, like avocado oil and aloe, that round out this non-greasy powerhouse of a product.
It’s Worth Noting
The cream is on the thinner side.
Product Details:
- Form: Cream
- Scent: Fragrance-free
- Key Ingredients: Salicylic acid (1.8%), coal tar extract, avocado oil, aloe vera, shea butter, provitamin B5
- Body Area: Arms, legs, body
How We Selected
To determine our top picks, we considered key ingredients, user reviews, price points, and accessibility. We also spoke with board-certified dermatologists to learn more about the science behind psoriasis treatment. When possible, we prioritized products suitable for sensitive skin—avoiding synthetic fragrances and dyes, as these ingredients can further irritate psoriasis-prone skin.
During the selection process, we prioritized products containing salicylic acid and coal tar, two ingredients approved by the FDA to treat psoriasis. We also looked for products rich in moisturizers, such as avocado oil, aloe vera, and shea butter. Finally, we sought out products that include vitamins and antioxidants to help protect the skin from environmental damage.
Our Experts
We also spoke to skin care experts to discuss what to look for when selecting psoriasis lotions. Experts we spoke to included:
- Brandon Cometti, MD, founder of Roswell Skin Care in Roswell, New Mexico
- Olivia Choi, MD, Ph.D., FAAD, a board-certified dermatologist and medical director of Dermatology at Janssen Pharmaceutical Companies of Johnson & Johnson
Who We Are
Lindsay Modglin is a nurse, public health professional, and Health.com writer who covers the rapidly evolving health and medical field. She enjoys researching and writing about the latest health, wellness, and medical technology developments. Her goal is to help readers make actionable and informed decisions about the products and services they use to improve their lives.