How Magnesium Affects Weight Loss Efforts

Closeup of a Black woman standing in her bathroom wearing a pink shirt, holding a white supplement pill in one hand and a glass of water in the other

Goodboy Picture Company / Getty Images

Magnesium is the fourth most abundant mineral in the human body, involved in more than 300 reactions that keep the body running smoothly. These reactions include protein synthesis, energy metabolism, muscle and nerve function, and blood pressure and blood sugar regulation.

Research suggests that adequate magnesium intake may support weight loss by optimizing some of these critical processes. Understanding the connection between magnesium and weight loss, as well as how to incorporate magnesium into your diet, may enhance your weight loss efforts and improve your overall health.

Role of Magnesium in Weight Loss

While more research is needed to establish a direct link between magnesium intake and weight loss, magnesium influences certain bodily processes involved in weight management.

Involved in Energy Production and Metabolism

Magnesium is an essential component of energy production. It plays a pivotal role in the metabolism of adenosine triphosphate (ATP), the primary molecule for storing and transferring energy in cells.

For ATP to become active, it must bind to magnesium to form a magnesium-ATP complex. This complex helps facilitate several metabolic processes, including those involved in energy production. As a result, magnesium enhances energy utilization, helping the body use and burn energy more efficiently.

Magnesium may also help with weight loss by affecting how the intestines process dietary fats. When magnesium binds with fats, it forms what are known as soaps—compounds that the body can’t easily absorb. Therefore, less fat is digested and used for energy, helping to reduce caloric intake and support weight loss.

Regulates Blood Sugar

Magnesium may support weight loss by aiding in blood sugar regulation.

Research has revealed that magnesium assists in maintaining stable blood sugar levels by enhancing the body’s ability to respond to insulin. Insulin is the hormone responsible for moving glucose (sugar) from the bloodstream into cells.

When the body’s cells effectively respond to insulin, it is referred to as insulin sensitivity. Conversely, when the body fails to respond to insulin, resulting in high glucose levels in the bloodstream, this condition is called insulin resistance.

With insulin resistance, the body compensates for the high amount of glucose in the blood by producing more insulin. Elevated insulin levels may lead to increased body fat storage. Increased magnesium intake may aid weight loss by improving insulin sensitivity and reducing blood glucose levels, preventing insulin resistance and excess body fat storage.

Reduces Inflammation

Chronic (long-term) inflammation is one of the underlying mechanisms involved in weight gain and obesity. 

Studies have shown that obesity is characterized by a state of prolonged, low-grade inflammation driven by the release of inflammatory molecules from adipose (fat) tissue. One inflammatory marker commonly elevated in individuals with obesity is C-reactive protein (CRP).

Magnesium intake and supplementation have been shown to dampen chronic inflammation associated with obesity. Research indicates that increased magnesium intake can help regulate inflammatory pathways and reduce the production of inflammatory molecules, particularly CRP.

How Magnesium Affects Appetite

Magnesium may help curb appetite.

Some evidence suggests that magnesium stimulates the small intestines to release a hormone called cholecystokinin (CCK). CCK is known for its ability to suppress hunger and reduce food intake. By increasing CCK levels, magnesium may help promote feelings of fullness, mitigate overeating, and reduce body weight. 

Similarly, magnesium’s assistance in regulating blood sugar levels may help reduce sudden blood sugar spikes and sharp crashes. When blood sugar levels are balanced, you are less likely to experience extreme hunger and cravings that may lead to overconsumption of foods high in added sugar.

Affect of Magnesium Deficiency

Although magnesium deficiency is rare, nearly 50% of people in the United States do not consume enough magnesium each day.

This is mainly due to the standard Western diet, which consists of a high intake of processed foods and demineralized water, with low amounts of legumes and vegetables. Additionally, many plant foods are often grown in magnesium-deficient soils. 

However, low magnesium levels can also be the result of preexisting conditions that impair magnesium absorption, such as celiac disease and inflammatory bowel disease (IBD). Magnesium depletion may also be present in individuals with colon cancer and renal disorders. 

Studies show that inadequate magnesium intake and magnesium deficiency can contribute to the development of obesity. Consuming magnesium-rich foods and supplements may help lower body fat and reduce the risk of obesity.

How To Incorporate Magnesium Into a Weight Loss Plan

To prevent magnesium deficiency and support weight loss, aim to get the recommended daily amounts of magnesium as follows:

  • Adult male: 400-420 milligrams (mg)
  • Adult female: 310-320 mg
  • During pregnancy: 350-360 mg
  • During lactation: 310-320 mg

You can get magnesium by consuming mineral-rich water and a wide variety of green leafy vegetables, legumes, nuts, seeds, and whole grains. These foods include:

  • Pumpkin seeds (1 ounce): 156 mg of magnesium
  • Chia seeds (1 oz): 111 mg
  • Almonds (1 oz): 80 mg
  • Boiled spinach (1/2 cup): 78 mg
  • Cashews (1 oz): 74 mg
  • Soy milk (1 cup): 61 mg
  • Black beans (½ cup): 60 mg
  • Edamame (½ cup): 50 mg
  • Peanut butter (2 tablespoons): 49 mg
  • Potato, with skin (3.5 oz): 43 mg
  • Brown rice (½ cup): 42 mg
  • Yogurt (1 cup): 42 mg

While it's best to obtain magnesium from food sources, magnesium supplements are also available in various forms to fill any nutritional gaps. Among the different types, magnesium in the citrate, aspartate, lactate, and chloride forms are more easily absorbed than magnesium sulfate and oxide.

Before adding one of these magnesium forms to your supplement cupboard, check the label to ensure the dose doesn’t exceed the safe limit of 350 milligrams. High doses of magnesium are associated with side effects, such as diarrhea, nausea, and stomach cramps.

Other Tips for Weight Management 

Boosting your magnesium intake won’t lead to weight loss on its own. Combining well-balanced dietary changes with consistent lifestyle habits is the most effective way to achieve your weight loss goals.

Several strategies proven to support weight management include:

  • Consume more fiber-rich foods: Dietary fiber, found in fruits, vegetables, whole grains, nuts, and seeds, helps promote feelings of fullness and aid in weight loss.
  • Make protein a priority: Protein promotes satiety and reduces appetite. It also helps preserve lean muscle mass, which helps you burn more calories at rest. 
  • Limit added sugar intake: Consuming too many sugar-sweetened beverages, desserts, snacks, and bars can lead to weight gain. Try to limit sugar intake to no more than 10% of your total caloric intake. 
  • Engage in physical activity: Ideally, adults should aim for 150 minutes of moderate-intensity aerobic exercise each week and dedicate at least two days to muscle-strengthening activities. 
  • Get enough sleep: It’s recommended that adults receive at least seven to nine hours of sleep each night to help maintain a healthy body weight.

A Quick Review

Magnesium, one of the most abundant minerals in the human body, is essential for various bodily processes that may support weight management. Some of these processes include assisting in energy production, regulating blood sugar, lowering inflammation, and controlling appetite.

However, over half of people in the United States do not get the recommended magnesium intake. Research shows insufficient magnesium intake and magnesium deficiency may contribute to the onset of obesity. Consuming magnesium-rich foods or taking a supplement when necessary can help maintain adequate magnesium levels.

Along with getting enough magnesium, consuming a well-balanced diet that contains fiber and protein and limits added sugar can also support weight loss. Prioritizing lifestyle habits like physical activity and sleep can also support overall health and weight management.

Edited by
Hannah Harper
Hannah Harper is an associate editor at Health.
Hannah Harper is a wellness editor for Health. Previously, she was an associate editor, assistant editor, and editorial assistant for Health. She covers topics on nutrition, women's health, and more.
Was this page helpful?
20 Sources
Health.com uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. National Institutes of Health: Office of Dietary Supplements. Magnesium.

  2. Askari M, Mozaffari H, Jafari A, Ghanbari M, Darooghegi Mofrad M. The effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2021;61(17):2921-2937. doi:10.1080/10408398.2020.1790498

  3. Lu L, Chen C, Yang K, et al. Magnesium intake is inversely associated with risk of obesity in a 30-year prospective follow-up study among American young adults. Eur J Nutr. 2020;59(8):3745-3753. doi:10.1007/s00394-020-02206-3

  4. Tardy AL, Pouteau E, Marquez D, Yilmaz C, Scholey A. Vitamins and minerals for energy, fatigue and cognition: A narrative review of the biochemical and clinical evidence. Nutrients. 2020;12(1):228. doi:10.3390/nu12010228

  5. Hosseini Dastgerdi A, Ghanbari Rad M, Soltani N. The therapeutic effects of magnesium in insulin secretion and insulin resistance. Adv Biomed Res. 2022;11:54. doi:10.4103/abr.abr_366_21

  6. Freeman AM, Acevedo LA, Pennings N. Insulin Resistance. In: StatPearls. StatPearls Publishing; 2024.

  7. Kolb H, Kempf K, Röhling M, Martin S. Insulin: too much of a good thing is bad. BMC Med. 2020;18(1):224. doi:10.1186s12916-020-01688-6

  8. Morais JBS, Severo JS, de Alencar GRR, et al. Effect of magnesium supplementation on insulin resistance in humans: A systematic review. Nutrition. 2017;38:54-60. doi:10.1016/j.nut.2017.01.009

  9. Ellulu MS, Patimah I, Khaza'ai H, Rahmat A, Abed Y. Obesity and inflammation: the linking mechanism and the complications. Arch Med Sci. 2017;13(4):851-863. doi:10.5114/aoms.2016.58928

  10. Khanna D, Khanna S, Khanna P, Kahar P, Patel BM. Obesity: A chronic low-grade inflammation and its markers. Cureus. 2022;14(2):e22711. doi:10.7759/cureus.22711

  11. Veronese N, Pizzol D, Smith L, Dominguez LJ, Barbagallo M. Effect of magnesium supplementation on inflammatory parameters: A meta-analysis of randomized controlled trials. Nutrients. 2022;14(3):679. doi:10.3390/nu14030679

  12. Kreft S, Štrukelj B. Influence of magnesium sulphate on cholecystokinin, hunger, and obesity. Progr Nutr. 2021;23(3). doi.org/10.23751/pn.v23i3.9081

  13. Wyatt P, Berry SE, Finlayson G, et al. Postprandial glycaemic dips predict appetite and energy intake in healthy individuals. Nat Metab. 2021;3(4):523-529. doi:10.1038/s42255-021-00383-x

  14. Piuri G, Zocchi M, Della Porta M, et al. Magnesium in obesity, metabolic syndrome, and type 2 diabetes. Nutrients. 2021;13(2):320. doi:10.3390/nu13020320

  15. Miketinas DC, Bray GA, Beyl RA, Ryan DH, Sacks FM, Champagne CM. Fiber intake predicts weight loss and dietary adherence in adults consuming calorie-restricted diets: The POUNDS lost(preventing overweight using novel dietary strategies) study. J Nutr. 2019;149(10):1742-1748. doi:10.1093/jn/nxz117

  16. Moon J, Koh G. Clinical evidence and mechanisms of high-protein diet-induced weight loss. J Obes Metab Syndr. 2020;29(3):166-173. doi:10.7570/jomes20028

  17. Cava E, Yeat NC, Mittendorfer B. Preserving Healthy Muscle during Weight Loss. Adv Nutr. 2017;8(3):511-519. doi:10.3945/an.116.014506

  18. Centers for Disease Control and Prevention. Be Smart About Sugar.

  19. Centers for Disease Control and Prevention. Tips for Maintaining Healthy Weight.

  20. Centers for Disease Control and Prevention. About Sleep.

Related Articles