Health Conditions A-Z Cardiovascular Disorders Heart Disease How Many Cups of Coffee Is Too Much? By Samantha Lauriello Samantha Lauriello Samantha Lauriello is a social media strategist and editor. She was previously an assistant editor at Health before moving over to Travel + Leisure as a social media editor. health's editorial guidelines Updated on November 21, 2024 Medically reviewed by Amelia MacIntyre, DO Medically reviewed by Amelia MacIntyre, DO Amelia MacIntyre, DO is a board certified family medicine physician and medical officer. learn more In This Article View All In This Article How Much Caffeine Is in a Cup of Coffee? Side Effects Risks Benefits Tips for Consuming Caffeine valentinrussanov / Getty Images It's generally safe to drink about four 8-ounce (oz) cups of coffee, which contain about 400 milligrams (mg) of caffeine, per day. More than this amount might be too much. You may feel anxious, jittery, or nauseous if you drink too much coffee. Drinking coffee has some benefits. Caffeine has antioxidants and anti-inflammatory compounds that may protect against Alzheimer's disease, heart disease, and liver disease. How Much Caffeine Is in a Cup of Coffee? Caffeine is a substance that's found in more than 60 plants, such as coffee beans and tea leaves. It tastes bitter and is an active ingredient in coffee. There are about 95 to 200 mg of caffeine in an 8-oz cup of coffee. Side Effects of Too Much Coffee Consuming the amount of caffeine in your regular coffee habit is likely safe. The side effects of too much caffeine may begin to develop after consuming moderate amounts. The amount of caffeine needed to cause unwanted side effects varies: People can have different levels of sensitivity to caffeine. Moderate side effects of too much caffeine include: Facial flushing Feelings of anxiety or restlessness Having to urinate more frequently Increased heart rate Stomach upset More severe side effects after significant amounts of caffeine can be dangerous. These side effects include feeling disorientated and experiencing hallucinations. Risks Up to 400 mg of caffeine—about four 8-oz cups of coffee—per day is typically safe for adults. Drinking more than this amount can increase the risk of health complications. Some people are more sensitive than others to the effects of caffeine. Consuming a lot of coffee can also negatively affect heart health and pregnancy. Caffeine Sensitivity You might feel jittery, irritable, or nauseous if you drink a lot of coffee. Some people may be more sensitive to caffeine than others. A study published in 2019 looked at what participants had a specific gene variant called CYP1A2. This variant helps people metabolize caffeine faster than those without it. People with the gene can't safely drink more coffee than those who don't. Heart Disease Heart disease is the leading cause of death worldwide. A study published in 2019 found that drinking six or more cups of coffee per day may increase the risk of heart disease by up to 22%. Large quantities of coffee can cause high blood pressure, which is a risk factor for heart disease. Pregnancy Complications Caffeine can cross the placenta and have negative effects on fetal development during pregnancy. It's a stimulant that raises heart rate and metabolism, which can affect the fetus. Research has shown that drinking too much coffee during pregnancy can increase the risk of low birth weight, miscarriage, and stillbirth. The American College of Obstetricians and Gynecologists (ACOG) advises that you limit your caffeine intake if you're pregnant. Consume no more than 200 mg of caffeine or one 12-oz cup of coffee per day. Benefits of Drinking Coffee Research has found numerous health benefits of drinking coffee. Coffee is a source of antioxidants, which can help lower the risk of several diseases. Some evidence suggests that coffee may lower the risk of the following: Alzheimer's disease: This is the most common type of dementia. Research has shown that the antioxidants in coffee may protect the brain against Alzheimer's disease. Cancer: Coffee has been shown to reduce the risk of some cancers, such as prostate and endometrial cancer. It may also protect against melanoma, the most severe type of skin cancer. Heart disease: Coffee is a source of phenols. These compounds have antioxidant and anti-inflammatory properties that can protect against heart disease. Some evidence suggests that one to three cups of coffee per day may reduce the risk of high blood pressure. Liver disease: Research has found that coffee may protect against cirrhosis (scarring of the liver) and liver cancer. The compounds found in coffee may decrease inflammation and support liver function. Parkinson's disease: Some evidence suggests that caffeine may block adenosine A2A receptors, which are expressed in people with Parkinson's disease. Tips for Consuming Caffeine It's generally safe to drink no more than four 8-oz cups of coffee per day. You may reduce your caffeine intake if you have: Acid reflux or stomach ulcers Chronic headaches Fast or irregular heart rhythm High blood pressure Painful, lumpy breasts Sleep problems Stress or anxiety Make sure to slowly reduce your caffeine intake to avoid caffeine withdrawal. Symptoms can include headaches, irritability, and nausea. A Quick Review Drinking coffee is generally safe if you do so in moderation. You can safely drink about 400 mg of caffeine, or four 8-oz cups of coffee, per day. Any more than this amount may be too much. You may develop side effects like anxiety and nausea if you drink too much coffee. Other health risks include increased blood pressure and pregnancy complications. Was this page helpful? Thanks for your feedback! Tell us why! Other Submit 14 Sources Health.com uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Wikoff D, Welsh BT, Henderson R, et al. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol. 2017;109(Pt 1):585-648. doi:10.1016/j.fct.2017.04.002 Evans J, Richards JR, Battisti AS. Caffeine. In: StatPearls. StatPearls Publishing; 2024. dePaula J, Farah A. Caffeine consumption through coffee: Content in the beverage, metabolism, health benefits and risks. Beverages. 2019;5(2):37. doi:10.3390/beverages5020037 Poole R, Kennedy OJ, Roderick P, et al. Coffee consumption and health: Umbrella review of meta-analyses of multiple health outcomes. BMJ. 2017;359:j5024. doi:10.1136/bmj.j5024 MedlinePlus. Caffeine. Zhou A, Hyppönen E. Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: A prospective analysis of up to 347,077 individuals and 8368 cases. Am J Clin Nutr. 2019;109(3):509-516. doi:10.1093/ajcn/nqy297 World Health Organization. Cardiovascular diseases. MedlinePlus. Caffeine in the diet. Brito Nunes C, Huang P, Wang G, et al. Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth. Int J Epidemiol. 2023;52(1):165-177. doi:10.1093/ije/dyac121 American College of Obstetricians and Gynecologists. How much coffee can I drink while I'm pregnant? Ikram M, Park TJ, Ali T, et al. Antioxidant and neuroprotective effects of caffeine against Alzheimer’s and Parkinson’s disease: insight into the role of NRF-2 and A2AR signaling. Antioxidants (Basel). 2020;9(9):902. doi:10.3390/antiox9090902 Miranda AM, Steluti J, Fisberg RM, et al. Association between coffee consumption and its polyphenols with cardiovascular risk factors: a population-based study. Nutrients. 2017;9(3):276. doi:10.3390/nu9030276 Wadhawan M, Anand AC. Coffee and liver disease. J Clin Exp Hepatol. 2016;6(1):40-46. doi:10.1016/j.jceh.2016.02.003 Ishibashi K, Miura Y, Wagatsuma K, et al. Adenosine A2A receptor occupancy by caffeine after coffee intake in Parkinson's disease. Mov Disord. 2022;37(4):853-857. doi:10.1002/mds.28897